Objective To evaluate childhood fever management education program for parents. Methods This cross-sectional study was to evaluate knowledge of patents on management of fever in their children. Participants were parents or caregivers of children aged 0-5 years whose children were admitted at Nakornping Hospital during June 1 to July 31, 2016. Participants completed a questionnaire about their knowledge and practices of fever in children before and after a one-to-one teaching on childhood fever management by registered nurses. The teaching activities included lectures, demonstrations and practices. The evaluation was done at both before and after the teaching using the same written questionnaire. The questionnaire was comprised of true or false questions (true=1, false=0). Data were analyzed using descriptive statistics, paired t-test and ANOVA. Results There were 62 parents or caregivers of the children admitted with fever participated in the study. Most of them (88.7%) were mothers of the children with average age of 28 years. The mean age of children was 1.91 years. On the evaluation of participants’ knowledge, the most incorrect answers reported both before and after one-to-one teaching were ‘dose size of antipyretic drug to be given for treatment’ (40% and 34.4%, respectively). The mean knowledge score of participant’s post-test was signi fi cantly higher than the pretest one (t=12.25, p<0.001). It was found on the pre-test that Thai ethnic participants and those with Civil Servant Medical Bene fi t Scheme tended to have signi fi - cantly higher knowledge scores than other ethnics and other health insurance scheme (F=18.87, p<0.01 and F=6.45, p<0.01, respectively) but these differences were not shown in the post test score. Conclusion This researchers’ development of childhood fever management education program for parents can be used successfully in this study. After the guidance from nurses, participants have about the same level of knowledge and practices regardless of their background. Guideline for managing fever in children should be widely disseminate to public for self-help which can be the fi rst step to reducing the overloaded healthcare system related to this common symptom